Guides
Deep answers to the questions founders, researchers, and R&D leaders actually ask about AI-driven materials science — grounded in the AIMS methodology: 78 filed provisional patents, ~1,275 claims, 40 scientific domains.
What Is AI-Driven Materials Discovery?
How AI inverts the discovery workflow — specify the outcome, search for the material — and where constraint-satisfaction fits among the main approaches.
How Do AI Agents Accelerate Scientific Literature Review?
Mapping the published landscape, extracting constraints, and killing bad premises early — plus how to keep agents from hallucinating the literature.
Computational Screening vs Lab Experimentation: Which Comes First?
Why screening is a search instrument and the lab is a proof instrument — and what the minimum viable experiment changes about R&D budgets.
How to Build an IP Portfolio With AI Research Agents
The Validate → Protect → License → Spin Out loop, step by step: verify premises, screen by constraints, falsify, map white space, file provisionals first.
What Does Materials R&D Actually Cost?
Why traditional discovery is priced in institutions, and how agent-assisted screening restructures the cost curve — including the published GNoME comparison.
7 Mistakes That Kill AI-for-Science Projects
Unverified premises, unaudited citations, single-property optimization, no falsification step — the failure modes and the pipeline stages that prevent them.
Can AI Actually Generate Patentable Inventions?
The law (Thaler v. Vidal, USPTO 2024 guidance), the human-contribution requirement, and how AIMS structures its process so the output is ownable.
How to Falsify AI-Generated Scientific Claims
Citation audits, primary-source tracing, structured adversarial attack, expert review, and the killing experiment — the gauntlet every claim must survive.
Interested in partnering on AIMS research?
We're seeking institutional research partners — universities, national laboratories, and corporate R&D teams — to advance these discoveries from computation to experimental validation.
Reach Out via Make More Marbles